SAT screening
At the heart of our medical solutions lies an analytical assay for screening the subcutaneous adipose tissue. Analysis is done by real-time PCR based on transcript cDNA. We developed completely new SOPs which allow handling of minimal samples of adipose tissue. The assay can be adapted to specific use cases.
Our mRNA panel
We use a basic panel of four mRNAs, namely HMGA2, PPAR-gamma, ADIPOQ and IL-6. These mRNAs are in the centre of controlling the energy metabolism in the adipose tissue. With regard to specific diagnostic questions or specific therapy-options further values or other drivers of pathology can be integrated.
Diagnostics, prognostics, therapeutics
For diagnostics and prognostics, the assay in itself provides the product, i.e., the marketable solution. For therapeutics the assay works as companion diagnostics as well as for therapy control. In our research the assay is the main instrument for developing new interventional concepts and validating their effectiveness.
Proven Technologies
Based on established technologies and using existing and well established reagents the tested and frozen SOPs allow an easy, quick and fail-safe handling.
Breaking new ground for
diagnostics, therapeutics and prevention
Diagnostics
mRNA-analysis of the SAT offers deep and completely new insights into the energy metabolism. Especially with metabolic diseases the current dynamics of the body and influences over life-time play a far greater role than genetic dispositions
Read moreTherapeutics
The key to successful treatment of metabolic diseases lies in the intervention with disease-causing on-going biological processes. As the mRNA of the SAT are to a great extent the drivers of pathology of these diseases, they offer a strong lever for therapy.
Read morePrevention
A great advantage of mRNA-analysis of the subcutaneous adipose tissue lies in the very early detection of unhealthy developments of the metabolism long before any signs can be seen in blood-analysis or any symptoms become apparent. It is, therefore, a powerful component in preventive personalised medicine.
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